The Apo E gene is the number one factor affecting how your body uses “The Big Three” food groups—carbohydrates, fats, and proteins. It is imperative to eat the right balance of carbohydrates, fats and proteins for your specific Apo E genotype since it influences your susceptibility of developing certain diseases.
The Apo E Gene Diet is not a diet in the usual sense of the word. The word “diet” refers to a series of recommendations for individual nutrition and other environmental factors, such as exercise, stress levels, to name a few. The goal is disease prevention and healthier life.
Introduction to the Apo E Gene
We all have the Apo E gene. This gene plays a key role in our body’s internal environment and influences the development of chronic disease, especially heart and Alzheimer’s disease. The Apo E gene occurs as three variations in humans: Apo E 2, Apo E 3, and Apo E 4. Since genes come in matching pairs, we each have two of every gene, one from each parent. If you received an Apo E 2 from one parent and an Apo E 3 from the other parent, your genotype would be E 2/3. There are six possible combinations of Apo E gene pairs.
How Your Apo E Genotype Affects Your Health
The specific pair of Apo E genes you inherited from your parents greatly influences your predisposition to certain illnesses, including heart disease, vascular dementia, Alzheimer’s disease, Parkinson’s disease, and cancer. For example, persons with the Apo E 4/4 genotype could have up to a 90% chance of developing a chronic illness such as Alzheimer’s disease.Maintaining an optimal diet and lifestyle for your particular Apo E genotype is known as a “gene-supportive environment” (GSE). Doing so can dramatically reduce your risk of developing these chronic illnesses.
The Apo E Gene Diet
The foundation of the Apo E Gene Diet is a nutritional plan that focuses on eating the optimal percentages of The Big Three food groups for your specific Apo E genotype. One diet does not fit all because each Apo E genotype processes foods differently. There is a unique optimal combination of carbohydrates, fats, and proteins in the ideal diet for each of the six Apo E genotypes. Creating this optimal balance in your diet provides the foundation for your good health.
Most of the existing dietary recommendations are based on the assumption that one diet is appropriate for everyone. These diets fail to accomplish long-term weight loss or optimal disease prevention because we are not all the same. In reality, diet and exercise recommendations must be individualized, beginning with a person’s genetic foundation.
By Dr. Seema Kanwal, ND
Balance Medical Center